Choline glycerophosphate 是脑磷脂生物合成的前体，能够提高胆碱在神经组织中的生物利用度。它对认知功能有显著影响，同时具有良好的耐受性和安全性，因此能够用于阿尔茨海默病和痴呆症的研究。

Glycerylphosphorylcholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia. Glycerylphosphorylcholine rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter. It is a non-prescription drug in most countries due to its Generally Recognised As Safe (GRAS) status [1]. Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer's disease. An Italian multicentre clinical trial on 2, 044 patients suffering from recent stroke were supplied Glycerylphosphorylcholine in doses of 1, 000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance [2].

28319-77-9

C8H20NO6P

257.223

Choline Alfoscerate;Choline glycerophosphate;甘磷酸胆碱;Alpha-GPC;Glycerophosphocholine;L-α-GPC;Glycerophosphorylcholine

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years