YS-370 是一种具有口服活性的 P-gp 抑制剂，对 CYP3A4 有中度抑制作用。 YS-370 有效逆转对紫杉醇和秋水仙碱的多药耐药性，与紫杉醇联合应用表现出更强的抗肿瘤活性。

YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combination with paclitaxel.

2470908-79-1

C37H35BrN4O3

663.60

DMSO:6 mg/mL (9mM),ultrasonic and warming and heat to 80°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years