Acetamiprid 是广泛使用的新烟碱类杀虫剂,是一种烟碱型乙酰胆碱受体激动剂,与神经肌肉和生殖系统疾病有关。
产品描述
Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders.
体内活性
Acetamiprid decreases in body weight and mildly affected spermatogenesis [1]. Acetamiprid disrupts subsequent testosterone biosynthesis by decreasing the rate of conversion of cholesterol to testosterone and by preventing cholesterol from entering the mitochondria within the Leydig cells. These effects caused reproductive damage to the rats[2]. Acetamiprid decreases the expression of testosterone-metabolism genes, nAChR subunit genes, and proliferation-associated genes in mice[1].
Cas No.
135410-20-7
分子式
C10H11ClN4
分子量
222.67
储存和溶解度
DMSO:97 mg/mL (435.62mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years