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Asoxime dichloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Asoxime dichloride图片
CAS NO:34433-31-3
包装与价格:
包装价格(元)
2 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
HI-6
Asoxime (dichloride)
Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate
产品介绍
Asoxime dichloride 是乙酰胆碱受体 (AChRs) 拮抗剂,包括烟碱受体,α7 乙酰胆碱受体。Asoxime dichloride 参与调节免疫应答。Asoxime dichloride 可作为抗原使用,改善神经系统的免疫效果。

产品描述

Asoxime dichloride is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system. Asoxime dichloride involves in modulating immunity response.

体内活性

A combination of HI-6 and keyhole limpet hemocyanin (KLH) produces a vaccination of almost the same efficacy as that for Freund's complete adjuvant[1]. Asoxime dichloride (intramuscular injection into the rear limb; 2% and 0.2% of median lethal dose 15.6 and 1.56 mg/kg; 21 or 65 days) significantly improved vaccination efficacy as a dose-dependent manner when KLH is 1 mg/kg[1].

Cas No.

34433-31-3

分子式

C14H16ClN4O3

分子量

323.76

别名

HI-6;Asoxime (dichloride);Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate

储存和溶解度

H2O:10 mg/mL (27.8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years