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Glycopyrrolate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:596-51-0
包装与价格:
包装价格(元)
10 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Gastrodyn
格隆溴铵
Robinul
Glycopyrrolate bromide
Glycopyrronium bromide
产品介绍
Glycopyrrolate 是一种毒蕈碱拮抗剂,在某些胃肠道疾病中用作解痉剂,并与某些麻醉剂一起减少唾液分泌。

产品描述

Glycopyrrolate is a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics.

体外活性

Glycopyrrolate inhibits EFS-induced contraction of guinea-pig trachea and human airways in a concentration-dependent manner. In competition studies, glycopyrrolate binds human peripheral lung and human airway smooth muscle (HASM) muscarinic receptors with affinities in the nanomolar range (Ki values 0.5–3.6?nM). Glycopyrrolate showed no selectivity in its binding to the M1–M3 receptors. Kinetics studies show that glycopyrrolate dissociates slowly from HASM muscarinic receptors[1].

Cas No.

596-51-0

分子式

C19H28BrNO3

分子量

398.33

别名

Gastrodyn;格隆溴铵;Robinul;Glycopyrrolate bromide;Glycopyrronium bromide

储存和溶解度

H2O:72 mg/mL (180.8 mM)
Ethanol:55 mg/mL (138.1 mM)
DMSO:60 mg/mL (150.6 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years