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Oxotremorine sesquifumarate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxotremorine sesquifumarate图片
CAS NO:17360-35-9
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品介绍
Oxotremorine sesquifumarate 是一种毒蕈碱受体激动剂,对 M2 的激活作用更强,可用于神经学研究。

产品描述

Oxotremorine sesquifumarate is a muscarinic receptor agonist.

体外活性

Oxotremorine (10.5 micron) produced a paralytic effect on twitch responses of rat diaphragm in vitro to direct and indirect stimulation[1].

体内活性

Rats with signs of neuropathy were subjected to SCS applied in awake, freely moving condition. Oxotremorine was administered intrathecally. Tactile, cold and heat sensitivities were assessed by using von Frey filaments, cold spray and focused radiant heat, respectively. Oxotremorine i.t. dose-dependently suppressed the tactile hypersensitivity. SCS markedly increased withdrawal thresholds (WTs), withdrawal latencies and cold scores[2].

Cas No.

17360-35-9

分子式

C12H18N2O·3/2C4H404

分子量

380.39

储存和溶解度

DMSO:<28mg>H2O:<8 mgml(21.03 mm)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years