Ciclopirox ethanolamine是一种合成的抗真菌剂,可研究浅表真菌病。
产品描述
Ciclopirox Olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
体内活性
对于白色念珠菌菌株SC5314(MIC80=1.0-2.0μg/ mL)和 烟曲霉菌株B5233(IC50=4.22 μM),Ciclopirox能够抑制生长。
细胞实验
Sabouraud glucose medium (2%) is used for cell culture growth, and RPMI 2% glucose medium and 2% Sabouraud glucose medium are used for MIC determinations. For cell culture growth curves, 220 mL of 2% Sabouraud glucose medium containing different concentrations of Ciclopirox are inoculated with 105 cells/mL, and the mixture is shaken at 160 rpm and 37 °C for 1-10 hours. Growth is measured photometrically at 630 nm. FeCl3 or 2,2'-bipyridine is added to the medium at different concentrations for inhibition studie(Only for Reference)
Cas No.
41621-49-2
分子式
C14H24N2O3
分子量
268.357
别名
环吡酮乙醇胺盐;环吡司胺;Ciclopirox ethanolamine
储存和溶解度
DMSO:6 mg/mL (22.35 mM)
Ethanol:28 mg/mL (104.3 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years