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Pyridoclax
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pyridoclax图片
CAS NO:1651890-44-6
包装:200 mg
市场价:9606元

产品名称
MR-29072
产品介绍

产品描述

Pyridoclax is an inhibitor of potential Mcl-1.

体外活性

Pyridoclax directly binds to Mcl-1. Pyridoclax induces apoptosis in combination with Bcl-xL-targeting siRNA or with ABT-737 in ovarian, lung, and mesothelioma cancer cells. Pyridoclax causes apoptosis in ovarian, and also in lung, and mesothelioma cancer cells when it is administrated in combination with Bcl-xL-targeting siRNA or Bcl-xL targeting molecules such as ABT-737 or its orally available derivative ABT-263. Pyridoclax sensitizes ovarian carcinoma cells to Bcl-xL-targeting strategies [1][2].

Cas No.

1651890-44-6

分子式

C29H22N4

分子量

426.51

别名

MR-29072

储存和溶解度

DMSO:20 mg/mL (46.89 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years