TCPOBOP 是一种组成型雄烷受体激动剂,可诱导强大的肝细胞增殖和肝肿大。它通过改变 BCL-2 蛋白来减少 Fas 诱导的小鼠肝损伤。
产品描述
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins.
体内活性
TCPOBOP (p.o.; 3 mg/kg; 1-5 days) obviously enhances Liver weight to body weight in LW/BW ratio at 48 hours [1].
Cas No.
76150-91-9
分子式
C16H8Cl4N2O2
分子量
402.06
储存和溶解度
DMSO:25 mg/mL (62.18 mM),ultrasonic and warming and heat to 50°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years