2-HBA 是姜黄素的合成类似物,是通过 Keap1-Nrf2-ARE 途径催化解毒反应的酶的间接诱导剂。
产品描述
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
体外活性
2-HBA doubles the specific activity of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) in Hepa1c1c7 cells at 0.15 μM[1]
Cas No.
131359-24-5
分子式
C17H14O3
分子量
266.296
储存和溶解度
DMSO:100 mg/mL (375.53 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years