M50054 是一种有效的细胞凋亡抑制剂,可用于研究抗 Fas 抗体引起的肝炎和化疗引起的脱发。它抑制 Etoposide 诱导的 U937 细胞 Caspase-3 活化,IC50为 79 μg/mL。
产品描述
Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.
体外活性
Apoptosis Inhibitor was identified as a novel inhibitor of apoptosis (programmed cell death) using an in vitro cell death assay system induced in human Fas-expressing WC8 cells by soluble human Fas ligand.
Cas No.
54135-60-3
分子式
C13H16O4
分子量
236.26
别名
2,2′-亚甲基双(1,3-环己二酮)
储存和溶解度
DMSO:9 mg/mL(38.09mM)
H2O:0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years