(Rac)-Acolbifene 是 EM652 的外消旋形式，具有抗雌激素和雌激素活性。

(Rac)-Acolbifene is a racemic form of EM652 with anti-estrogenic and estrogenic activities.

In T-47D cells, (Rac)-Acolbifene (0.110 nM) inhibits cell growth with an IC50 value of 0.110 nM[1].

In ovariectomized mice, (Rac)-Acolbifene (7.5 nM, 75 nM; oral) shows shows 63% and 84% antiuterotrophic inhibitions, respectively[1].

151533-34-5

C29H31NO4

457.56

EM-343;(Rac)-EM-652;阿考比芬

DMSO:90 mg/mL (196.7 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years