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Gigantol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gigantol图片
CAS NO:67884-30-4
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Gigantol 是一种联苄基化合物,从几种药用兰花中获得,是一种Wnt/β-CATenin通路抑制剂,具有抗肿瘤活性。

产品描述

Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows the protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway.Gigantol also shows α-glucosidase inhibitory activity.

Cas No.

67884-30-4

分子式

C16H18O4

分子量

274.316

储存和溶解度

DMSO:50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years