IQ1 有多种作用，如保持小鼠ESCs的多功能性、降低Wnt刺激的磷酸化、阻止PP2A/Nkd的相互作用等等。

Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates expression of Oct4 and Sox2 transcription factors. Binds to serine/threonine phosphatase PP2A and prevents PP2A/Nkd interaction.

331001-62-8

C21H22N4O2

362.433

IQ1;IQ-1

Ethanol:7 mg/mL (19.31 mM)
DMSO:72 mg/mL (198.66 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years