CAY10526 是 mPGES-1 的选择性抑制剂，可抑制 NF-Κb 信号通路。

CAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.

CAY10526 dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 1.8 μM without any effect on COX-2 expression[1].

938069-71-7

C12H7BrO3S

311.15

CAY 10526;BTH;CAY-10526

DMSO:16 mg/mL(51.43 mM)
DMF:16 mg/mL(51.43 mM)
Ethanol:1 mg/ml(3.21 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years