PROStaglandin E1 是一种前列腺素受体配体，对小鼠EP1、EP2、EP3、EP4和IP的Ki值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集，可作为血管扩张剂用于外周血管疾病的研究。

Alprostadil is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP.

745-65-3

C20H34O5

354.48

列腺素E1;前列地尔;PGE1;Alprostadil

Ethanol:17.7 mg/mL (50 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years