FLT3-IN-4 是一种口服有效的 Fms 样酪氨酸受体激酶 3 (FLT3; IC50= 7 nM) 抑制剂,可用于急性髓性白血病的研究。
产品描述
FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenous leukemia.
体外活性
FLT3-IN-4 shows potent inhibitory activities against Molm-13 and MV4-11 cells with IC50 values 0.022±0.003nM and 0.089±0.001 nM , respectively[1].
Cas No.
2304799-09-3
分子式
C23H25N7O2
分子量
431.49
别名
FLT3 inhibitor 9u
储存和溶解度
DMSO:22.5mg/mL (52.1mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years