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Procainamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Procainamide图片
CAS NO:51-06-9
包装与价格:
包装价格(元)
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品名称
Biocoryl
Novocainamide
产品介绍
Procainamide 是 DNA 甲基转移酶 1 (DNMT1) 的特异性强效抑制剂。Procainamide是一种 1A 类抗心律失常药物。Procainamide 具有研究癌症和心律失常的潜力。

产品描述

Procainamide is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias [1] [2].

体外活性

HCT116, HCT116 DNMT1–/–, and HCT116 DNMT3b–/– cells were treated with PBS, pH 7.4 or 0.5 mM procainamide for 96 h. Procainamide treatment of HCT116 DNMT3b–/– cells decreased m5dC content by 11.5%, but treatment of HCT116 DNMT1–/– cells did not decrease m5dC content. These results suggested that DNMT1 was the intracellular target of procainamide[1].

Cas No.

51-06-9

分子式

C13H21N3O

分子量

235.33

别名

Biocoryl;Novocainamide

储存和溶解度

DMSO:45mg/mL (191.2mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years