Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).

Imetit dihydrobromide (2.5-10 mg/kg; i.p.) causes the licking response which is induced by Apomorphine[4].

32385-58-3

C6H12Br2N4S

332.06

VUF 8325 dihydrobromide;SKF 91105 dihydrobromide

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years