Tesmilifene fumarate 是一种H1C受体拮抗剂，可增强化疗的细胞毒性且保护正常细胞。

Tesmilifene fumarate (DPPE fumarate) is an H1C receptor antagonist。

Tesmilifene may modulate the effects of 12(S)HETE in cancer cells that influence the susceptibility of cellular DNA to chemotherapy indirectly[1].

Tesmilifene (DPPE, 20 mg/kg (s.c.) and 20 μg (icv in 5 μL)) potentiated seizures induced by both convulsants[2].

1185241-83-1

C23H29NO5

399.48

DPPE fumarate

DMSO:248 mg/mL (620.81 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years