Bilastine是新型抗组胺药，对H1组胺受体具有高度选择性，起效快，作用时间长的特性，可用于变应性鼻结膜炎和荨麻疹。

Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.

Bilastine has a highly selective affinity for the H1-receptor but a very low affinity for 30 other tested receptors. It isn't obvious inhibitory against bradykinin, serotonin, muscarinic M3-receptors, leukotriene D4, calcium, α1-adrenoceptors, β2-adrenoceptors, and H2- and H3- receptors.

In patients with allergic rhinoconjunctivitis, Bilastine is efficacious in all nasal symptoms including obstruction and in eye symptoms. In the fasting state, Bilastine is quickly absorbed, but the absorption is slowed when it is taken with food or fruit juice.

202189-78-4

C28H37N3O3

463.622

比拉斯汀;Bilaxten

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years