L-NIO dihydrochloride induces a consistentfocal ischemic infarctin rats. L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively.

L-NIO is a non-selective,potent and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively.

L-NIO ?causes focal cerebral ischemia in the adult rat brain.

159190-44-0

C7H16ClN3O2

209.67

DMSO:33.33 mg/mL (135.42 mM),Need ultrasonic
H2O:50 mg/mL (203.14 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years