Cyfluthrin 属于 II 型拟除虫菊酯，对多种昆虫都有杀灭效果。Cyfluthrin是Nav1.8钠通道调节剂。它可应用于农业、兽医、杀虫剂、拟除虫菊酯和贮存产品等领域。

Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.

Cell viability MTT assay was carried out to assess cyfluthrin cytotoxicity; IC30 and IC50 values for cyfluthrin were calculated to be 4.81 ± 0.92 μM and 19.39 ± 3.44 μM, respectively. Cyfluthrin increased significantly gene expressions of apoptosis, proinflammation and oxidative stress (Bax, Bcl-2, Casp-3, BNIP3, AKT1, p53, APAF1, NFκB1, TNFα and Nrf2) mediators. In the most genes, the mRNA levels induced by cyfluthrin were partially reduced by MEL (1 μM)[1].

68359-37-5

C22H18Cl2FNO3

434.29

Chloroform:Slightly soluble
Methanol:Heated
Powder: -20°C for 3 years
In solvent: -80°C for 2 years