您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Aminoguanidine hydrochloride
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Aminoguanidine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aminoguanidine hydrochloride图片
CAS NO:1937-19-5
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Pimagedine
Guanyl hydrazine
氨基胍盐酸盐
Imino semicarbazide
CP-12009-18 tartrate
肼甲酰亚胺酰胺一氯化氢(氨基胍盐酸盐)
Pimagedine hydrochloride
Hydrazinecarboximidamide
产品介绍
Aminoguanidine hydrochloride 是二胺氧化酶抑制剂,也是一氧化氮合酶抑制剂,可用于糖尿病肾病的研究。

产品描述

Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.

体内活性

Aminoguanidine ameliorates neonatal hypoxic-ischemic brain damage and that temporal profiles of NO correlated with the neuroprotective effect of aminoguanidine. Neuroprotection by AG is attributable to suppression of NO produced by iNOS after the end of the hypoxic period, during the reoxygenation phase. The half-life of AG is estimated to be between 6 and 8 h in vivo and approximately 4.4 h in human with normal renal function.AG is also an inhibitor of the formation of advanced glycation end products. Systematically administered advanced glycation end product–modified BSA increases cerebral infarct size in an adult rat, which is attenuated by AG[2].

Cas No.

1937-19-5

分子式

CH7ClN4

分子量

110.55

别名

Pimagedine;Guanyl hydrazine;氨基胍盐酸盐;Imino semicarbazide;CP-12009-18 tartrate;肼甲酰亚胺酰胺一氯化氢(氨基胍盐酸盐);Pimagedine hydrochloride;Hydrazinecarboximidamide

储存和溶解度

Ethanol:<1 mgml
DMSO:21 mg/mL (190 mM)
H2O:20 mg/mL (180.9 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years