7-Ethoxyresorufin 是细胞色素 P450 (尤其是CYP1A1) 的荧光底物和竞争性抑制剂,同时对 NO 合酶具有抑制作用。
产品描述
7-Ethoxyresorufin (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.
体内活性
7-ER inhibited responses to NO and nitrergic nerve stimulation through generation of superoxide radicals. A 7-ER sensitive P450 system may be involved in the bioactivation of GTN and SNP in rat aortic rings, but not in rabbit aorta or rat anococcygeus muscles.
Cas No.
5725-91-7
分子式
C14H11NO3
分子量
241.246
别名
乙氧基试卤灵;Resorufin ethyl ether
储存和溶解度
DMF:1.92 mg/mL (8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years