Poly(I:C) 是toll样受体3 (TLR3)激动剂,是一种合成的双链 RNA (dsRNA)。它存在于一些病毒中,可用于模拟细胞外 dsRNA的作用。
产品描述
Poly (I:C) is a synthetic double-stranded RNA (dsRNA) analog and is an immunostimulant that acts as the most potent interferon (IFN) inducer. It also is a Toll-like receptor- 3 (TLR3) agonist.
体外活性
Mixtures that included the TLR7/8 agonists R848 or CL075, combined with the poly (I:C) can produce 3-d mature dendritic cells [2].
Cas No.
24939-03-5
分子式
C19H27N7O16P2
分子量
671.4
别名
聚胞苷酸;Poly(I:C)
储存和溶解度
H2O:≥21.5mg/mL
DMSO:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years