产品描述
SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.
体内活性
In CK-p25 mice, SRT3657 (30 mg/kg; i.g.; daily; for 6 weeks) activates SIRT1 . SRT3657 treatment prevents synaptic and neuronal loss and effectively rescues against neurodegeneration-driven memory impairments. SRT3657 recapitulates the neuroprotective potential of caloric restriction (CR).
Cas No.
1383551-17-4
分子式
C40H54N8O6S
分子量
774.97
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years