SRT1460 是一种有效的SIRT1激动剂,其EC1.5值为 2.9 μM。
产品描述
SRT1460 is a SIRT1 activator.
体外活性
SRT1460 inhibited cell growth and survival of pancreatic cancer cells[1].
细胞实验
Patu8988t (pancreatic cancer cells), Panc-1 (pancreatic cancer cells), SU86.86 (pancreatic cancer cells), HPDE cells.?Concentration:2 μM, 4 μM, 6 μM.?Incubation Time:72 hours[1]
Cas No.
925432-73-1
分子式
C26H29N5O4S
分子量
507.61
别名
3,4,5-三甲氧基-N-(2-(3-(哌嗪-1-基甲基)咪唑并[2,1-B]噻唑-6-基)苯基)苯甲酰胺;SRT1460
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years