ROSiglitazone maleate 是一种选择性PPARγ激活剂，具有抗糖尿病特性和潜在抗肿瘤活性。它也是TRP通道调节剂，可抑制 TRPM2、TRPM3 的活性，激活 TRPC5。

Rosiglitazone Maleate is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.

在许多细胞系中,Rosiglitazone能够抑制胆固醇合成。在AMPKα亚基内,Rosiglitazone激活含有α1和α2的AMPK复合物,能够增加磷酸化。

155141-29-0

C22H23N3O7S

473.50

马来酸罗格列酮;BRL 49653C;BRL 49653

Ethanol:<1 mgml
DMSO:87 mg/mL (183.9 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years