8-Azaguanine 是一种具有潜在抗肿瘤活性的嘌呤类似物。它易于掺入核糖核酸中，干扰正常的生物合成途径，从而抑制细胞生长，可作为抗代谢药。

8-Azaguanine is a purine analogue with potential antineoplastic activity.

A study of the in vivo metabolism of 8-azaguanine-2-C 14 by mouse neoplasms that are susceptible or resistant to growth inhibition by 8-azagnanine have been reported. The results show that the growth of those neoplasms which convert significant amounts of 8-azaguanine to 8-azaguanylic acid is inhibited by 8-azaguanine.

134-58-7

C4H4N6O

152.117

Azaguanine-8;NSC-749;SK 1150;8-氮鸟嘌呤;SF-337

Ethanol:<1 mgml
DMSO:6 mg/mL (39.44 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years