SIBA 是 SAH 的合成类似物,可作为 S-腺苷甲硫氨酸介导的甲基转移的抑制剂。它干扰多种酶活性,可逆地阻断单纯疱疹病毒 1 型病毒的繁殖。
产品描述
SIBA is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic activities in vitro, such as SAH hydrolase, methylthioadenosine phosphorylase and cAMP phosphodiesterase. SIBA reversibly blocks the multiplication of herpes simplex type 1 virus (HSV)
Cas No.
35899-54-8
分子式
C14H21N5O3S
分子量
339.41
别名
5'-Isobutylthioadenosine;5ˊ-异丁硫基-5ˊ-脱氧腺苷;5'-Deoxy-5'-isobutylthioadenosine
储存和溶解度
DMSO:90 mg/mL (265.17 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years