您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Ganciclovir sodium
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Ganciclovir sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ganciclovir sodium图片
CAS NO:107910-75-8
包装与价格:
包装价格(元)
25 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
2'-Nor-2'-deoxyguanosine sodium
更昔洛韦钠
BW 759 sodium
RS-21592 sodium
Cytovene IV sodium
产品介绍
Ganciclovir sodium 是核苷类似物和口服抗病毒药物,具有抗病毒活性,尤其是针对巨细胞病毒和单纯疱疹病毒 1 型。

产品描述

Ganciclovir Sodium is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).

体外活性

Ganciclovir showed activity against feline herpesvirus type-1 (FHV-1, IC50 = 5.2 microM)[1].

体内活性

In adult rats, the intracochlear diffusion of ganciclovir was shown to achieve the same concentration as in blood. In gestating mice, transplacental diffusion was observed, with a fetal-to-maternal blood ratio of 0.5. In newborn mice, the plasma concentration profile of ganciclovir showed a peak at 2 h followed by a gradual decrease. In adult mice, the concentration peaked at 1 h, but became undetectable by 2 h after injection. Counts of white blood cells, red blood cells and platelets decreased significantly in ganciclovir-treated newborn mice[3].

Cas No.

107910-75-8

分子式

C9H13N5NaO4

分子量

278.22

别名

2'-Nor-2'-deoxyguanosine sodium;更昔洛韦钠;BW 759 sodium;RS-21592 sodium;Cytovene IV sodium

储存和溶解度

DMSO:4 mg/mL (14.43 mM)
H2O:40 mg/mL (144.29 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years