MK-4827 Racemate 是一种选择性 PARP1 和 PARP2 抑制剂，IC50 分别为 3.8 nM 和 2.1 nM，对 PARP3、V-PARP 和 Tank1 的选择性超过 330 倍。

MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.

1038915-75-1

C19H20N4O

320.39

Niraparib Racemate;2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide

DMSO:60 mg/ml (187.27 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years