PARP1-IN-8是PARP1的有效抑制剂（IC50 = 97 nM）。

PARP1-IN-8 is an effective inhibito of PARP1 (IC50 = 97 nM).

PARP1-IN-8 (0, 0.1, 1, 10 μM; 24, 48 h) showed significantly potent anti-proliferative activity against A549 cells and didn’t display any significant cytotoxicity on HFF cells[1].

836640-15-4

C23H18ClN3O2

403.87

N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide

DMSO:60 mg/mL (148.57 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years