HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα).

HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cell apoptosis with low toxicity in vivo.

2271413-06-8

C28H38N8O5

566.65

DMSO:32.5 mg/mL (57.35 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years