NITD-2 是一种登革病毒 (DENV) 聚合酶抑制剂，可抑制 DENV RdRp 介导的 RNA 延伸。
产品描述
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.
体外活性
NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration.NITD-2 inhibits de novo RNA synthesis[1].
Cas No.
1197896-79-9
分子式
C23H19N3O4S
分子量
433.48
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
m.cnreagent.com