产品描述
(Rac)-Nedisertib is a racemate of Nedisertib, a potent inhibitor of DNA-PK(IC50 of<3 nM).
体外活性
(Rac)-Nedisertib potently inhibits DNA-PK with an IC50 of<3 nM for DNA-PK, 0.5-5 μM for cellular pDNA-PK and 15-25 μM for KV11.1 (hERG, human ether a-go-go related gene).
Cas No.
1637542-34-7
分子式
C24H21ClFN5O3
分子量
481.91
别名
(Rac)-M3814
储存和溶解度
DMSO:100 mg/mL (207.51 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years