ETP-45658 是一种PI3K抑制剂，抑制PI3Kα、PI3Kδ、PI3Kβ和PI3Kγ的IC50值分别为 22.0、39.8、129.0 和 717.3 nM。它可研究癌症，还抑制DNA-PK和mTOR，IC50分别为70.6 和 152 nM。

ETP 45658 is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively).

1198357-79-7

C16H17N5O2

311.34

ETP 45658;ETP45658

DMSO:60 mg/ml (192.72 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years