U18666A 是一种细胞渗透性药物，是一种胆固醇合成和转运抑制剂，抑制埃博拉病毒，登革热病毒和人类丙型肝炎病毒的复制。

U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.

U18666A, the antiviral effect is found to result from retarded viral trafficking in the cholesterol-loaded late endosomes/lysosomes and suppressed de novo sterol biosynthesis in treated infected cells. It is also observed an additive antiviral effect of U18666A with C75, a fatty acid synthase inhibitor [1][2].

3039-71-2

C25H42ClNO2

424.06

DMSO:50 mg/mL (117.91 mM),Need ultrasonic
H2O:10 mg/mL (23.58 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years