Src Inhibitor 3 是一种有效的 c-terminal Src 激酶抑制剂（CSK HTRF 中 IC50<3 nM，Caliper 中 IC50<4 nM）。 Src Inhibitor 3 增加由 T 细胞受体信号传导诱导的 T 细胞增殖。

Src Inhibitor 3 is an effective inhibitor of c-terminal Src kinase (IC50<3 nM in CSK HTRF,<4 nM in Caliper assay). Src Inhibitor 3 increases T cell proliferation induced by T cell receptor signaling.

Src Inhibitor 3 (oral) reduces inhibitory LCK phosphorylation in vivo and shows the ability to enhance T cell activation in response to antigen stimulation[1].

2380027-49-4

C34H32ClFN8O4

671.12

DMSO:95 mg/mL (141.55 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years