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Eberconazole nitrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eberconazole nitrate图片
CAS NO:130104-32-4
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
硝酸依柏康唑
Ebernet
产品介绍
Eberconazole nitrate 是一种二氯咪唑衍生物,具有抗真菌活性,效果比Ketoconazole、Clotrimazole和Miconazole强。它通过局部给药对皮肤癣菌病具有潜在的研究价值。

产品描述

Eberconazole Nitrate is an azole antifungal agent and broad-spectrum imidazole derivative.

体内活性

Spherical and porous Eberconazole Nitrate(EB) microsponge particles were obtained.?The optimized microsponges possessed particle size, drug content and entrapment efficiency of 24.5 μm, 43.31% and 91.44%, respectively.?Microsponge-loaded gels demonstrated controlled release, nonirritancy to rat skin and antifungal activity.?An in vivo skin deposition study demonstrated fourfold higher retention in the stratum corneum layer as compared with commercial cream[1].

动物实验

Eberconazole Nitrate(EB) microsponges were prepared using the quasiemulsion solvent diffusion method.?The effect of formulation variables (drug:polymer ratio, internal phase volume and amount of emulsifier) and process variables (stirring time and stirring speed) on the physical characteristics of microsponges were investigated.?The optimized microsponges were dispersed into a hydrogel and evaluated[1].

Cas No.

130104-32-4

分子式

C18H15Cl2N3O3

分子量

392.24

别名

硝酸依柏康唑;Ebernet

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years