Hexyl gallate 是没食子酸的烷基酯衍生物，对恶性疟原虫具有很强的抗疟活性，IC50为 0.11 mM。它具有抗菌活性，通过抑制 RhlR 抑制鼠李糖脂和绿脓杆菌素的产生。

Hexyl gallate, an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).

Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) inhibits only Rhl-dependent production of rhamnolipid and pyocyanin by inhibiting RhlR, without affecting elastase production and biofilm formation which are regulated by the Las system.Hexyl gallates inhibits pigment production at 10-30 μM, but also exhibited antibacterial activity. Hexyl gallates also exhibits antibacterial activity against CV026 cells. Hexyl gallates inhibits only N-butanoyl homoserine lactone (BHL) production at 100 and 300 μM without affecting N-(3-oxododecanoyl)-l-homoserine lactone (OdDHL) and 2-heptyl-3-hydroxy-4(1 H) quinolone (PQS) production[1]. Hexyl gallates is an antimicrobial alternative to copper compounds that inhibits Xanthomonas citri growth in a dose-response manner, showing a more pronounced activity at the range of 30-50 μg/ml, and it targets the membrane of X. citri[3].

1087-26-9

C13H18O5

254.28

Gallic acid hexyl ester;Hexyl 3,4,5-trihydroxybenzoate;没食子酸己酯

DMSO:40 mg/mL (157.30 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years