BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC50 of 5 nM. (From patent WO2019033119A1)[1].

1619923-32-8

C54H59ClF4N6O8S4

1159.78

DMSO:200 mg/mL (172.45 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years