SpiNOSin 是一种具有神经保护作用的 C-糖苷类黄酮，从Zizyphus jujube种子分离得到，能够激活 Nrf2/HO-1 通路，并抑制 Aβ1-42的产生和聚合。

1. Spinosin ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.

72063-39-9

C28H32O15

608.549

斯皮诺素;Flavoayamenin

Ethanol:Soluble
DMSO:91 mg/mL(149.5 mM)
Pyridine, Methanol, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years