Swertiaperennin is a natural product

Three known xanthones were isolated from the crude methanolic extract of the roots: gentiacaulein, gentiakochianin, and Swertiaperennin. The first two showed a vasorelaxing activity in rat aortic preparations, pre-contracted by 3 microM norepinephrine (pIC50 = 5.00 +/- 0.032 for gentiacaulein, pIC50 = 4.95 +/- 0.068 for gentiakochianin), 20 mM KCl (pIC50 = 4.90 +/- 0.15 for gentiacaulein; 4.59 +/- 0.069 for gentiakochianin), or 5 mM caffeine; on the contrary, in the same conditions, Swertiaperennin did not show any vasodilator effect.

22172-17-4

C15H12O6

288.25

甲基当药宁;Swertiaperennin

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years