Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).

Corynoxine B, a natural autophagy inducer, restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA [1].

Corynoxine B exhibited prolongation of the thiopental-induced hypnosis on oral administration in mice [2].

17391-18-3

C22H28N2O4

384.47

柯诺辛碱 B;柯诺辛碱B

DMSO:80 mg/mL (208.07 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years