Corynoxeine是从钩藤中分离的一种天然产物，是 PDGF-BB 诱导血管平滑肌细胞 (VSMCs) 增殖过程中的ERK1/ERK2抑制剂。

1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.

630-94-4

C22H26N2O4

382.46

DMSO:69 mg/mL(180.4 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years