Rhyncholphylline 是一种生物碱类化合物，从钩藤中分离得到，具有很高的生物活性，被广泛用于抗炎、神经保护等方面的研究。

1. Rhynchophylline can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.

76-66-4

C22H28N2O4

384.476

Mitrinermine;Rhynchophyllin;Mitrinermin;钩藤碱;Rhyncophylline

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years