Isocorynoxeine 是钩藤中的一种生物碱，剂量依赖性抑制5-HT2A受体介导的电流反应，IC50为 72.4 μM。

1. Isocorynoxeine shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant neuroprotective effect against glutamate-induced HT22 cell death at the maximum concentration.

51014-29-0

C22H26N2O4

382.46

异去氢钩藤碱;7-Isocorynoxeine

DMSO:70 mg/mL(183 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years