Monotropein 是从Morinda officinalis中获得，能够抑制硫酸葡聚糖硫酸钠诱导的结肠炎小鼠模型中炎性因子的表达。

1. Monotropein has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. 4. Monotrope ininhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages.

5945-50-6

C16H22O11

390.341

Monotropeine;水晶兰苷

Pyridine, Methanol, etc.:Soluble
Ethanol:Insoluble
DMSO:71 mg/mL(181.9 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years